Statistical evidence to support that liver flush works to lower bilirubin levels.
My husband had elevated bilirubin levels since as early as we can trace back on his medical records during his 20s. But it was first brought to our attention in his 30s, when he was diagnosed with Gilbert’s Syndrome by our family doctor in 2012. In 2013, my husband performed the first of a series of liver flushes in attempt to address this issue. I compiled over 10 years of lab test evidence to illustrate that liver flush worked to reduce and normalize my husband’s bilirubin levels.
I am not saying liver flush can cure every case of Gilbert’s Syndrome – I will elaborate below on the diagnosis and explain my point. I will also explain why we decided to use the liver flush method. By sharing our story, I hope if you are in a similar situation as my husband, our thought process and statistical evidence can help you find an appropriate solution.
The Diagnosis of Gilbert’s Syndrome
Around the time our first son was born, we switched to a new family doctor who could look after the birthing process. That was in the later part of 2009. My husband didn’t take a blood test with the new family doctor until 2012, when he was found to have a high level of bilirubin in the blood stream. Our family doctor suggested that my husband had Gilbert’s syndrome. She also told my husband that there is no treatment for Gilbert’s syndrome, the condition is common and there is nothing to worry about.
I looked up Gilbert’s syndrome, and learned that:
- Gilbert’s syndrome is a mild liver disorder in which the liver does not properly process bilirubin.
- The underlying cause is the lack of a specific liver enzyme to convert un-conjugated bilirubin to conjugated bilirubin due to the mutation in the UGT1A1 gene.
- Gilbert’s syndrome often is un-noticed until later childhood or early adulthood in people who has it.
- The diagnosis of Gilbert’s syndrome is based on the elevated level of un-conjugated bilirubin without evidence of other liver diseases.
Although my husband had higher-than-normal bilirubin levels, there was no testing to confirm gene mutation. I do understand that a genetic disorder of such leads to excess bilirubin in the blood. However, the reverse isn’t true – having elevated bilirubin levels doesn’t mean it must be a genetic disorder.
I noticed that the lab test only shows the count of total bilirubin in the blood, which is the combination of conjugated bilirubin and un-conjugated bilirubin. I am guessing because most of the bilirubin in blood stream is in the un-conjugated form, the doctors assume that un-conjugated bilirubin is high when the total bilirubin is high. I am not a doctor, so I don’t know if this assumption stands, or why the lab doesn’t test the 2 types of bilirubin separately. We will never know. I just think that in order to diagnose Gilbert’s syndrome according to protocol, at least un-conjugated bilirubin count should be clearly referenced.
Because un-conjugated bilirubin must be processed and converted in the liver to become conjugated bilirubin by a specific enzyme, I can only derive that higher un-conjugated bilirubin means there is either a genetic cause or a functional cause for this conversion to not work effectively. Once un-conjugated bilirubin is converted into conjugated bilirubin, conjugated bilirubin will then be removed from the liver through bile into the intestines. If conjugated bilirubin is high, I can only derive that there may be a blockage to prevent conjugated bilirubin from being carried out by the bile and eliminated from the body.
My husband had elevated total bilirubin. It may or may not be Gilbert’s syndrome. I don’t feel the blood test was conclusive.
Why We Decided to Try Liver Flush?
I thought there was high probability my husband had an issue with his liver functions. Maybe the effectiveness of that said enzyme was compromised because his liver wasn’t producing it at the capacity it should or due to other factors, or there was congestion in the liver that reduced bile flow. In any case, I believed he should cleanse his liver and boost his liver functions. I held a very opposite opinion as the doctor’s, and I believed his condition wasn’t harmless and we shouldn’t dismiss potential liver problems simply because the abnormal blood test result is common.
My husband had taken various liver support supplements on the market, which include herbs such as artichoke, sarsaparilla root, milk thistle, curcumin, etc. Nothing made a noticeable impact in his blood test results.
At that time, I had known about the amazing liver and gallbladder flush for many years. Intuitively I felt he needed to physically de-congest his liver by flushing out the bile ducts. My husband agreed to it. If you aren’t aware of the liver flush method, I wrote in depth about what it is for and how it works – read it here. It can even be used on children.
Statistics Before and After the Liver Flush
I was able to dig out lab test records from as early as 2007, the year we got married. I don’t have access to anything earlier, but based on the historical data I did find, I wouldn’t be surprised if my husband’s bilirubin level had been high for quite some time prior to 2007.

My husband performed his first liver flush in September 2013. He went in for a blood test the next month. We were impressed by the test result – October 2013 was the first time his total bilirubin dropped into the normal range, <22 µmol/L.
He did a few more liver flushes throughout the years after. He wasn’t following a schedule with the liver flush, although I think it would be more beneficial for him to keep up with the flush more regularly. Nonetheless, his bilirubin level in the following years were all in the normal range.
The statistics and the graph show a clear distinction before and after the liver flush.
Conclusion
My husband’s bilirubin level had been elevated for at least 6 years consistently before the liver flush. His bilirubin was completely normalized after his first liver flush, and maintained throughout the years while he continued cleansing his liver. The liver flush method worked. The numbers don’t lie.
In my husband’s case, I believe he was mis-diagnosed for Gilbert’s syndrome as he clearly did not have a genetic disorder. It’s also worth noting that many more people might have been mis-diagnosed given the diagnostic protocols the doctors are following, as stated above. We have to factor in family history, other illnesses and what indicators are actually relied on for such conclusion.
Whether you have a diagnosis of Gilbert’s syndrome or is simply told to have elevated bilirubin, it’s worth looking into the liver flush method. We develop many ailments through our life that we were not born with. I believe many health issues can be fixed if we bring our body back into balance; and they should be before manifesting into even bigger health crisis down the road.
In another blog post, you can find everything you need to know about the liver flush method my husband used.
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I have 3 of the 5 genetic variants that predispose to Gilbert’s Syndrome. Here is some positive information about the condition from https://www.geneticlifehacks.com/gilberts-syndrome/
Benefits of higher bilirubin levels in Gilbert’s Syndrome:
When bilirubin is elevated due to genetics, there are several noted benefits. These benefits are derived from bilirubin acting as an antioxidant, neutralizing excess ROS. Many of the benefits are seen more in older adults, around age 50, when the toll of excess oxidative stress is likely to cause many of the problems of aging.[ref]
Protection against Atherosclerosis:
The most significant benefit of higher bilirubin is a decrease in atherosclerotic plaque buildup. As you’ll see in the genotype report, the variants linked to higher bilirubin are also linked to a lower risk of heart disease.
Protection against Chronic Respiratory Diseases:
A UK study looked at Gilbert’s syndrome’s effect on respiratory disease risk in people born in 1946. Many people in this cohort had smoked, and those with Gilbert’s syndrome were less likely to have COPD or asthma than those with normal bilirubin.[ref]
Protection against fatty liver disease:
Animal studies show that the UGT1A1 variants that increase bilirubin also decrease the risk and severity of fatty liver disease (NAFLD).[ref] A meta-analysis including more than 100,000 participants found that higher bilirubin levels are associated with lower odds of NAFLD.[ref]
Overall decreased mortality:
A research study with over 4200 people with Gilbert’s syndrome and ~22,000 with normal bilirubin found that the mortality rate was decreased in Gilbert’s syndrome. The results showed the adjusted mortality rate was about 50% less in people with Gilbert’s syndrome.[ref]
Thus, the drawback of possibly having jaundice during times of physical stress is offset, for some people, with a reduced risk of cardiovascular disease, COPD, or liver disease.
Mildly higher billirubin might actually be quite positive. See the study:
Bilirubin acts as a multipotent guardian of cardiovascular integrity: more than just a radical idea
https://journals.physiology.org/doi/full/10.1152/ajpheart.00417.2017
I lowered mine by taking glucuronolactone. It’s not talked about much, but it is an ingredient used in energy drinks and also found in small amounts in kombucha tea. I purchased a large amount from a bulk supplement site on the web. Anyway, my levels were around 4-5 for my entire life (not quite as bad as mentioned in this article) and after using glucuronolactone they were in the normal range for the first time in my life. How it works is it conjugates bilirubin making it water soluble and excretes through the kidneys.
Hi there, I have had yellow eyes for years due to the high intake of sugar that I have previously had. Before that my eyes were white. I am so desperate to get rid of them, and i heard that the fault of yellow eyes was due to the build up of bilirubin and the toxins in my body. I went to get a blood test and they said that i was fine, but i believe that my actual bilirubin levels are most likely much higher than the recommended, as such, it is like your husbands. However, i am a healthy young male and i do not suffer any side effects from it, I just want to get whiter eyes :). In a week I will begin the journey and do my liver detox, I have been inspired by your article and I believe that it could really help me. Do you think that it could get rid of yellow eyes?
Thank you
how did it go? i am the same.. my levels r hight im wanting to try this i am a healthy 39 year old male
Hi there; I have been diagnosed with Gilbert Syndrome for quite some time and frankly I had little clue on the side effects until recently when I discovered that I have stones in my gallbladder! and while I was still shocked trying to understand what does that mean, the DR told me that I have to remove the gallbladder!
It was sad and funny that the DR has written papers already for patients of such cases and the bottom line, I don’t need the gallbladder and that I can live without it!
I did not accept this and I felt there must be a solution somewhere! I must say I felt so alone, not knowing where to go until I read the book “The Amazing Liver and Gallbladder Flush”. For the first time, I had a ray of hope and started searching the internet, I found your blog and this page in specific and it just made my day!
When I read about your husband’s case, I felt I am not alone; I want to thank you so much for writing such a post! It has given me the courage to continue this journey to heal myself.
Wish me best and thank you again.
Yours.
TJ
So great to hear that you are trying to take control of your health! I very much appreciate you sharing your stories. All the best on your healing journey.